Lab publications

Computational or AI paperGilestro GF*
The evolution of sex for artificial intelligence: a population-genetic framework for multigenerational model populations
preprint – arXiv 2026 Sep 16 / 2609.18560 [PDF]
Experimental biology paperGilestro GF*
Sleep elasticity: accessory, useful and vital components of a single state
preprint – EcoEvoRxiv 2026 Aug 19 / 10.32942/X22D71 [PDF]
Computational or AI paperFulcher BD, Lubba CH, Gilestro GF, Schultz SR, Jones NJ
Interpretable model-free inference of parametric variation across time-series data through large-scale feature extraction
preprint – arXiv 2026 Jun 11 / 2606.12836 [PDF]
Computational or AI paperGilestro GF*
Two errors in attributing intelligence and a Bayesian Turing test
preprint – philSci 2026 Feb 03 / 28098 [PDF]
Computational or AI paperGilestro GF*
AI reviewers are here — we are not ready
Nature 2025 Dec 3; 648(9)
Experimental biology paperGuo L, Ferretti V, Gilestro GF*
Sleep Deprivation Primes Synaptic Vulnerability Without Inducing Oxidative Damage: A Mechanistic Reappraisal
preprint – bioRxiv 2025 Sep 05 / 674430 [PDF]
Experimental biology paperGilestro GF*
Refining the sleep circuits one neuron at a time
PLOS Biology 2025 Apr 5; 23(4)
Experimental biology paperJoyce M, Falconio AF#, Blackhurst L#, Prieto-Godino L, French AS*, and Gilestro GF*
Divergent evolution of sleep in Drosophila species
Nature Communications 2024 Jun 14; (15) 5091 [PDF]
Experimental biology paperPetzold A*, Gilestro GF*
ninna nanna links circadian and homeostatic sleep drive in Drosophila
preprint – bioRxiv 2024 May 13 / 593616 [PDF]
Experimental biology paperJones H, Willis JA, Firth LC, Giachello CNG, and Gilestro GF*
A reductionist paradigm for high-throughput behavioural fingerprinting in Drosophila melanogaster
eLife 2023 Nov 8; (12) RP86695 [PDF]
Computational or AI paperBlackhurst L*, Gilestro GF*
Ethoscopy & Ethoscope-lab: a framework for behavioural analysis to lower entrance barrier and aid reproducibility
Bioinformatics Advances 2023 Sep 20; 3(1) [PDF]
Experimental biology paperVincent CM, Beckwith EJ, Simoes da Silva CJ, Pearson WH, Kierdorf K, Gilestro GF, Dionne MS*
Infection increases activity via Toll dependent and independent mechanisms in Drosophila melanogaster
PLoS Pathog. 2022 Sep 21;18(9):e1010826
Experimental biology paperFrench A, Geissmann Q, BeckwithEJ and Gilestro GF*
Sensory processing during sleep in Drosophila melanogaster
Nature 2021 Oct 21; 598(3) [PDF]
Experimental biology paperGilestro GF*
Sleep: Imaging the Fly Brain Reveals New Paradoxes
Current Biology 2021 Feb 08; 31(3):R140-R142
Experimental biology paperBeckwith EJ*, French AS
Sleep in Drosophila and its context
Front Physiol. 2019 Sep 11;10:1167
Experimental biology paperGeissmann Q#, Beckwith EJ# and Gilestro GF*
Most sleep does not serve a vital function: Evidence from Drosophila melanogaster
Science Advances 2019 Feb 20; 5(2) eaau9253 [PDF]
Computational or AI paperGeissmann Q*, Garcia Rodriguez L, Beckwith EJ and Gilestro GF*
Rethomics: an R framework to analyse high-throughput behavioural data
PLoS ONE 2019 Jan 16; 14(1); e0209331 [PDF]
Computational or AI paperGeissmann Q, Garcia Rodriguez L, Beckwith EJ, French AS, Jamasb AR, and Gilestro GF*
Ethoscopes: an open platform for high-throughput ethomics
PLoS Biology 2017 Oct 19;15(10);e2003026. [PDF]
Experimental biology paperBeckwith EJ, Geissmann Q, French AS, and Gilestro GF*
Regulation of sleep homeostasis by sexual arousal.
eLife 2017 Sep 12;6;e27445. [PDF]
Computational or AI paperGilestro GF
Video tracking and analysis of sleep in Drosophila melanogaster
Nature Protocols 2012 Apr 26;7(5):995-1007. [PDF]
Computational or AI paperGilestro GF*, Cirelli C
pySolo: a complete suite for sleep analysis in Drosophila
Bioinformatics 2009 Jun 1;25(11):1466-7. [PDF]
Experimental biology paperGilestro GF, Tononi G, Cirelli C
Widespread changes in synaptic markers as a function of sleep and wakefulness in Drosophila
Science 2009 Apr 3;324(5923):109-12 [PDF]

Previous publications

Experimental biology paperGilestro GF
Redundant Mechanisms for Regulation of Midline Crossing in Drosophila
PLoS ONE, 2008 Nov 24;3(11):e3978.
Experimental biology paperDickson BJ* and Gilestro GF*
Regulation of Commissural Axon Pathfinding by Slit and its Robo receptors
Annu Rev Cell Dev Biol, 2006;22:651-75.
Experimental biology paperChristensen C, Ambartsumian N, Gilestro GF, Thomsen B, Comoglio PM, Tamagnone L, Guldberg P, and Lukanidin E
Proteolytic processing converts the repelling signal Sema3E into an inducer of invasive growth and lung metastasis
Cancer Research, 2005 Jul 15;65(14):6167-6177
Experimental biology paperArtigiani S, Conrotto P, Fazzari P, Gilestro GF, Barberis D, Giordano S, Comoglio PM and Tamagnone L
Plexin-B3 is a functional receptor for semaphorin 5A
Embo Reports, 2004 Jul;5(7):710-4
Experimental biology paperGiordano S, Corso S, Conrotto P,Artigiani S, Gilestro GF, Barberis D,Tamagnone L and Comoglio PM
The Semaphorin 4D Receptor controls invasive growth by coupling with Met tyrosine kinase
Nature Cell Biology, 2002 Sep;4(9):720-4
Experimental biology paperPetrelli A, Gilestro GF, Lanzardo S, Comoglio PM, Migone N and Giordano S
The Endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met
Nature, 2002 Mar 14;416(6877):187-90 [PDF]

(*) corresponding author.
(#) equal contribution.

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